Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials

Objective To explore the extent to which components of composite end points in randomised controlled trials vary in importance to patients, the frequency of events in the more and less important components, and the extent of variability in the relative risk reductions across components. Design Syste...

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Detalles Bibliográficos
Autores principales: Ferreira-González, Ignacio, Permanyer-Miralda, Gaiet, Domingo-Salvany, Antònia, Busse, Jason W, Heels-Ansdell, Diane, Montori, Victor M, Akl, Elie A, Bryant, Dianne M, Alonso-Coello, Pablo, Alonso, Jordi, Worster, Andrew, Upadhye, Suneel, Jaeschke, Roman, Schünemann, Holger J, Pacheco-Huergo, Valeria, Wu, Ping, Mills, Edward J, Guyatt, Gordon H
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group Ltd. 2007
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852019/
https://ncbi.nlm.nih.gov/pubmed/17403713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmj.39136.682083.AE
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