Oxidative Phenotype Protects Myofibers from Pathological Insults Induced by Chronic Heart Failure in Mice

The fiber specificity of skeletal muscle abnormalities in chronic heart failure (CHF) has not been defined. We show here that transgenic mice (8 weeks old) with cardiac-specific overexpression of calsequestrin developed CHF (50.9% decrease in fractional shortening and 56.4% increase in lung weight,...

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Detalhes bibliográficos
Main Authors: Li, Ping, Waters, Richard E., Redfern, Shelley I., Zhang, Mei, Mao, Lan, Annex, Brian H., Yan, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851852/
https://ncbi.nlm.nih.gov/pubmed/17255328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060505
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