A pentanucleotide repeat polymorphism in the 5' control region of the apolipoprotein(a) gene is associated with lipoprotein(a) plasma concentrations in Caucasians.

The enormous interindividual variation in the plasma concentrations of the atherogenic lipoprotein(a) [Lp(a)] is almost entirely controlled by the apo(a) locus on chromosome 6q26-q27. A variable number of transcribed kringle4 repeats (K4-VNTR) in the gene explains a large fraction of this variation,...

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Main Authors: Trommsdorff, M, Köchl, S, Lingenhel, A, Kronenberg, F, Delport, R, Vermaak, H, Lemming, L, Klausen, I C, Faergeman, O, Utermann, G
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC185183/
https://ncbi.nlm.nih.gov/pubmed/7615785
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