Metabolic abnormalities in skeletal muscle of patients receiving zidovudine therapy observed by 31P in vivo magnetic resonance spectroscopy.

Patients on long-term zidovudine (AZT) therapy experience muscle fatigue and weakness attributed to AZT-induced mitochondrial toxicity in skeletal muscle. To determine if the clinico-pathological abnormalities in these patients correspond to abnormal muscle energy metabolism, we used 31P in vivo mag...

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Detalhes bibliográficos
Main Authors: Sinnwell, T M, Sivakumar, K, Soueidan, S, Jay, C, Frank, J A, McLaughlin, A C, Dalakas, M C
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC185180/
https://ncbi.nlm.nih.gov/pubmed/7615782
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