Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

To test the hypothesis that nitric oxide (NO) limits endothelial activation, we treated cytokine-stimulated human saphenous vein endothelial cells with several NO donors and assessed their effects on the inducible expression of vascular cell adhesion molecule-1 (VCAM-1). In a concentration-dependent...

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Main Authors: De Caterina, R, Libby, P, Peng, H B, Thannickal, V J, Rajavashisth, T B, Gimbrone, M A, Shin, W S, Liao, J K
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC185173/
https://ncbi.nlm.nih.gov/pubmed/7542286
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