Fosfomycin inactivates its target enzyme in Escherichia coli cells carrying a fosfomycin resistance plasmid.

The target enzyme for fosfomycin antibiotic action, enolpyruvyl transferase, was synthesized in similar amounts and with similar kinetic and inhibition constants for phosphoenolpyruvate and fosfomycin, respectively, by an Escherichia coli strain containing the fosfomycin resistance plasmid pOU900 an...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	León, J, García-Lobo, J M, Ortiz, J M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1983
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6357073/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.2.276
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