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Effect of osmotic blood-brain barrier disruption on gentamicin penetration into the cerebrospinal fluid and brains of normal rabbits.

Rapid infusion of hyperosmolar solutions into the internal carotid artery transiently disrupts the blood-brain barrier, permitting entry of substances that are ordinarily excluded from the nervous system. This study compared gentamicin concentrations in the cerebrospinal fluid (CSF) and brain tissue...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Strausbaugh, L J, Brinker, G S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1983
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185128/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6416158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.2.147
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