Oral Prion Infection Requires Normal Numbers of Peyer’s Patches but Not of Enteric Lymphocytes

Prion pathogenesis following oral exposure is thought to involve gut-associated lymphatic tissue, which includes Peyer’s patches (PPs) and M cells. Recruitment of activated B lymphocytes to PPs requires α(4)β(7) integrin; PPs of β7(−/−) mice are normal in number but are atrophic and almost entirely...

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Autors principals: Prinz, Marco, Huber, Gerhard, Macpherson, Andrew J. S., Heppner, Frank L., Glatzel, Markus, Eugster, Hans-Pietro, Wagner, Norbert, Aguzzi, Adriano
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2003
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851248/
https://ncbi.nlm.nih.gov/pubmed/12651603
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