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Telomere Shortening and Cellular Senescence in a Model of Chronic Renal Allograft Rejection

Cellular senescence has been suggested to play a role in the deterioration of renal graft function and has been linked to telomere shortening. We have investigated markers of cellular senescence in the F344 to LEW rat model of chronic renal transplant rejection. Syngeneic and LEW to F344 transplants...

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Autori principali: Joosten, Simone A., van Ham, Vanessa, Nolan, Claire E., Borrias, Maria C., Jardine, Alan G., Shiels, Paul G., van Kooten, Cees, Paul, Leendert C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851231/
https://ncbi.nlm.nih.gov/pubmed/12651622
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