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Angiopoietin-Like 4 Is a Proangiogenic Factor Produced during Ischemia and in Conventional Renal Cell Carcinoma

Ischemic and solid tumor tissues are less well perfused than normal tissue, leading to metabolic changes and chronic hypoxia, which in turn promotes angiogenesis. We identified human angiopoietin-like 4 (angptl4) as a gene with hypoxia-induced expression in endothelial cells. We showed that the leve...

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Dettagli Bibliografici
Autori principali: Le Jan, Sébastien, Amy, Céline, Cazes, Aurélie, Monnot, Catherine, Lamandé, Noël, Favier, Judith, Philippe, Josette, Sibony, Mathilde, Gasc, Jean-Marie, Corvol, Pierre, Germain, Stéphane
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851201/
https://ncbi.nlm.nih.gov/pubmed/12707035
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