Amplification and Overexpression of the L-MYC Proto-Oncogene in Ovarian Carcinomas

Gene amplification is an important mechanism of oncogene activation in various human cancers, including ovarian carcinomas (OvCas). We used restriction landmark genomic scanning (RLGS) to detect amplified DNA fragments in the genomes of 47 primary OvCas. Visual analysis of the RLGS gel images reveal...

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Main Authors: Wu, Rong, Lin, Lin, Beer, David G., Ellenson, Lora H., Lamb, Barbara J., Rouillard, Jean-Marie, Kuick, Rork, Hanash, Samir, Schwartz, Donald R., Fearon, Eric R., Cho, Kathleen R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851191/
https://ncbi.nlm.nih.gov/pubmed/12707044
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