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Effect of discontinuous acyclovir treatment on in vitro reactivation of herpes simplex virus from latently infected trigeminal ganglia.

Exposing explant cultures of latently infected mouse trigeminal ganglia alternately to acyclovir-containing and drug-free medium led to a significant decrease in the proportion of ganglia containing reactivatable herpes simplex virus. The loss of virus from the explant cultures was not caused by the...

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Publicado en:Antimicrob Agents Chemother
Principais autores: Klein, R J, Friedman-Kien, A E, DeStefano, E
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1983
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185116/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6312871/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.1.129
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