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A Urokinase-Derived Peptide (Å6) Increases Survival of Mice Bearing Orthotopically Grown Prostate Cancer and Reduces Lymph Node Metastasis

The high rate of prostate cancer mortality invariably reflects the inability to control the spread of the disease. The urokinase-type plasminogen activator and its receptor (u-PAR) contribute to prostate cancer metastases by promoting extracellular matrix degradation and growth factor activation. Th...

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Bibliografiske detaljer
Main Authors: Boyd, Douglas D., Kim, Sun-Jin, Wang, Heng, Jones, Terence R., Gallick, Gary E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851141/
https://ncbi.nlm.nih.gov/pubmed/12547719
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