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Cellular Dysfunction in the Diabetic Fibroblast : Impairment in Migration, Vascular Endothelial Growth Factor Production, and Response to Hypoxia

Although it is known that systemic diseases such as diabetes result in impaired wound healing, the mechanism for this impairment is not understood. Because fibroblasts are essential for wound repair, we compared the in vitro behavior of fibroblasts cultured from diabetic, leptin receptor-deficient (...

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Main Authors: Lerman, Oren Z., Galiano, Robert D., Armour, Mary, Levine, Jamie P., Gurtner, Geoffrey C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851127/
https://ncbi.nlm.nih.gov/pubmed/12507913
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