Microarray analysis of newly synthesized RNA in cells and animals

Current methods to analyze gene expression measure steady-state levels of mRNA. To specifically analyze mRNA transcription, we have developed a technique that can be applied in vivo in intact cells and animals. Our method makes use of the cellular pyrimidine salvage pathway and is based on affinity-...

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Bibliografiska uppgifter
Huvudupphovsmän: Kenzelmann, M., Maertens, S., Hergenhahn, M., Kueffer, S., Hotz-Wagenblatt, A., Li, L., Wang, S., Ittrich, C., Lemberger, T., Arribas, R., Jonnakuty, S., Hollstein, M. C., Schmid, W., Gretz, N., Gröne, H. J., Schütz, G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2007
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851046/
https://ncbi.nlm.nih.gov/pubmed/17405863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610439104
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