A New Method to Extract Nuclei from Paraffin-Embedded Tissue to Study Lymphomas Using Interphase Fluorescence in Situ Hybridization

Fluorescence in situ hybridization (FISH) is difficult to accomplish using thin-sections of paraffin-embedded lymphoid tissue because of the high cellularity and truncated cells that interfere with accurate scoring of individual nuclei. We modified and tested a new technique to isolate individual nu...

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Main Authors: Paternoster, Sarah F., Brockman, Stephanie R., McClure, Rebecca F., Remstein, Ellen D., Kurtin, Paul J., Dewald, Gordon W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Technical Advances
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850824/
https://ncbi.nlm.nih.gov/pubmed/12057901
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