An Ethyl-Nitrosourea-Induced Point Mutation in Phex Causes Exon Skipping, X-Linked Hypophosphatemia, and Rickets

We describe the clinical, genetic, biochemical, and molecular characterization of a mouse that arose in the first generation (G(1)) of a random mutagenesis screen with the chemical mutagen ethyl-nitrosourea. The mouse was observed to have skeletal abnormalities inherited with an X-linked dominant pa...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Carpinelli, Marina R., Wicks, Ian P., Sims, Natalie A., O’Donnell, Kristy, Hanzinikolas, Katherine, Burt, Rachel, Foote, Simon J., Bahlo, Melanie, Alexander, Warren S., Hilton, Douglas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2002
Témata:
Animal Model
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850771/
https://ncbi.nlm.nih.gov/pubmed/12414538
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky