Frequent Fas Gene Mutations in Testicular Germ Cell Tumors

The Fas (Apo-1/CD95)/Fas ligand (L) system is involved in cell death signaling, and has been suggested to be important for the regulation of germ cell apoptosis in the testis. Mutations of the Fas gene may result in accumulation of germ cells and thus might contribute to testicular carcinogenesis. T...

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Main Authors: Takayama, Hitoshi, Takakuwa, Tetsuya, Tsujimoto, Yuichi, Tani, Yoichi, Nonomura, Norio, Okuyama, Akihiko, Nagata, Shigekazu, Aozasa, Katsuyuki
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2002
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850755/
https://ncbi.nlm.nih.gov/pubmed/12163388
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