The Mevalonate Pathway during Acute Tubular Injury : Selected Determinants and Consequences

Renal injury evokes tubular cholesterol accumulation, mediated in part by increased HMG CoA reductase (HMGCR) levels. The present study was undertaken to define potential molecular determinants of these changes and to ascertain the relative importance of increased cholesterol production versus meval...

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Main Authors: Zager, Richard A., Shah, Vallabh O., Shah, Hemangini V., Zager, Philip G., Johnson, Ali C. M., Hanson, Sherry
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2002
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850732/
https://ncbi.nlm.nih.gov/pubmed/12163393
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