Autoantibodies to Type VII Collagen Mediate Fcγ-Dependent Neutrophil Activation and Induce Dermal-Epidermal Separation in Cryosections of Human Skin

Epidermolysis bullosa acquisita is an autoimmune subepidermal blistering disease associated with autoantibodies to type VII collagen, the major constituent of anchoring fibrils. Previous attempts to demonstrate the blister-inducing potential of autoantibodies to this protein have failed. To address...

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Autors principals: Sitaru, Cassian, Kromminga, Arno, Hashimoto, Takashi, Bröcker, Eva B., Zillikens, Detlef
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2002
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850704/
https://ncbi.nlm.nih.gov/pubmed/12107115
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