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The α(2) Integrin Subunit-Deficient Mouse : A Multifaceted Phenotype Including Defects of Branching Morphogenesis and Hemostasis

The α(2)β(1) integrin is a collagen/laminin receptor expressed on platelets, endothelial cells, fibroblasts, and epithelial cells. To define the role of the α(2)β(1) integrin in vivo, we created a genetically engineered mouse in which expression of the α(2)β(1) integrin was completely eliminated. Mi...

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Bibliographic Details
Main Authors: Chen, Jianchun, Diacovo, Thomas G., Grenache, David G., Santoro, Samuel A., Zutter, Mary M.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850700/
https://ncbi.nlm.nih.gov/pubmed/12107118
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