SCOMP Is Superior to Degenerated Oligonucleotide Primed-Polymerase Chain Reaction for Global Amplification of Minute Amounts of DNA from Microdissected Archival Tissue Samples

Global genome amplification from formalin-fixed tissues is still problematic when performed with low cell numbers. Here, we tested a recently developed method for whole genome amplification termed “SCOMP” (single cell comparative genomic hybridization) on archival tissues of different ages. We show...

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Hauptverfasser: Stoecklein, Nikolas H., Erbersdobler, Andreas, Schmidt-Kittler, Oleg, Diebold, Joachim, Schardt, Julian A., Izbicki, Jakob R., Klein, Christoph A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2002
Schlagworte:
Technical Advances
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850686/
https://ncbi.nlm.nih.gov/pubmed/12107088
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