Expression of Geminin as a Marker of Cell Proliferation in Normal Tissues and Malignancies

Geminin interacts with a DNA replication initiation factor, Cdt1p, to suppress initiation of DNA replication in a Xenopus egg extract based cell-free system, leading to the expectation that the protein acts as an inhibitor of cell proliferation. Immunohistochemistry and immunoblotting for geminin, h...

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Main Authors: Wohlschlegel, James A., Kutok, Jeffery L., Weng, Andrew P., Dutta, Anindya
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2002
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850683/
https://ncbi.nlm.nih.gov/pubmed/12107111
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