Specific Allelic Loss of p16 (INK4A) Tumor Suppressor Gene after Weeks of Iron-Mediated Oxidative Damage during Rat Renal Carcinogenesis

Oxidative tissue damage has been shown to be associated with carcinogenesis. In human cancers p16(INK4A) is one of the most frequently mutated tumor suppressor genes. The present study used the ferric nitrilotriacetate (Fe-NTA)-induced rat renal carcinogenesis model to determine whether oxidative da...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Hiroyasu, Makoto, Ozeki, Munetaka, Kohda, Haruyasu, Echizenya, Michiko, Tanaka, Tomoyuki, Hiai, Hiroshi, Toyokuni, Shinya
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Investigative Pathology 2002
Θέματα:
Short Communications
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850668/
https://ncbi.nlm.nih.gov/pubmed/11839561
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