Retinal Vascular Endothelial Growth Factor Induces Intercellular Adhesion Molecule-1 and Endothelial Nitric Oxide Synthase Expression and Initiates Early Diabetic Retinal Leukocyte Adhesion in Vivo

Leukocyte adhesion to the diabetic retinal vasculature results in early blood-retinal barrier breakdown, capillary nonperfusion, and endothelial cell injury and death. Previous work has shown that intercellular adhesion molecule-1 (ICAM-1) and CD18 are required for these processes. However the relev...

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Main Authors: Joussen, Antonia M., Poulaki, Vassiliki, Qin, Wenying, Kirchhof, Bernd, Mitsiades, Nicholas, Wiegand, Stanley J., Rudge, John, Yancopoulos, George D., Adamis, Anthony P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850650/
https://ncbi.nlm.nih.gov/pubmed/11839570
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