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Quantitative Trait Loci Influence Renal Disease Progression in a Mouse Model of Alport Syndrome

Alport syndrome is a human hereditary glomerulonephritis which results in end-stage renal failure (ESRF) in most cases. It is caused by mutations in any one of the collagen α3(IV), α4(IV), or α5(IV) chain genes (COL4A3-COL4A5). Patients carrying identical mutations can exhibit very different disease...

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Hlavní autoři: Andrews, Kaya L., Mudd, Jacqueline L., Li, Cong, Miner, Jeffrey H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850644/
https://ncbi.nlm.nih.gov/pubmed/11839593
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