Inducible Expression of Vascular Endothelial Growth Factor in Adult Mice Causes Severe Proliferative Retinopathy and Retinal Detachment

Transgenic mice with vascular endothelial growth factor (VEGF) driven by the rhodopsin promoter (rho/VEGF mice) develop neovascularization that originates from the deep capillary bed of the retina and grows into the subretinal space. In rho/VEGF mice, VEGF expression in photoreceptors begins between...

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Detalhes bibliográficos
Main Authors: Ohno-Matsui, Kyoko, Hirose, Akira, Yamamoto, Satoru, Saikia, Jina, Okamoto, Naoyuki, Gehlbach, Peter, Duh, Elia J., Hackett, Sean, Chang, Michelle, Bok, Dean, Zack, Donald J., Campochiaro, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Animal Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850637/
https://ncbi.nlm.nih.gov/pubmed/11839592
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