Features of Colorectal Cancers with High-Level Microsatellite Instability Occurring in Familial and Sporadic Settings : Parallel Pathways of Tumorigenesis

High-level microsatellite instability (MSI-H) is demonstrated in 10 to 15% of sporadic colorectal cancers and in most cancers presenting in the inherited condition hereditary nonpolyposis colorectal cancer (HNPCC). Distinction between these categories of MSI-H cancer is of clinical importance and th...

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Autors principals: Young, Joanne, Simms, Lisa A., Biden, Kelli G., Wynter, Coral, Whitehall, Vicki, Karamatic, Rozemary, George, Jill, Goldblatt, Jack, Walpole, Ian, Robin, Sally-Anne, Borten, Michael M., Stitz, Russell, Searle, Jeffrey, McKeone, Diane, Fraser, Leigh, Purdie, David R., Podger, Kay, Price, Rachael, Buttenshaw, Ron, Walsh, Michael D., Barker, Melissa, Leggett, Barbara A., Jass, Jeremy R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2001
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850604/
https://ncbi.nlm.nih.gov/pubmed/11733361
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