Aortic Valve Endothelial Cells Undergo Transforming Growth Factor-β-Mediated and Non-Transforming Growth Factor-β-Mediated Transdifferentiation in Vitro

Cardiac valves arise from endocardial cushions, specialized regions of the developing heart that are formed by an endothelial-to-mesenchymal cell transdifferentiation. Whether and to what extent this transdifferentiation is retained in mature heart valves is unknown. Herein we show that endothelial...

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Hlavní autoři: Paranya, Gretchen, Vineberg, Sabrina, Dvorin, Evan, Kaushal, Sunjay, Roth, Stephen J., Rabkin, Elena, Schoen, Frederick J., Bischoff, Joyce
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850524/
https://ncbi.nlm.nih.gov/pubmed/11583961
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