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Mitochondrial Alterations Caused by Defective Peroxisomal Biogenesis in a Mouse Model for Zellweger Syndrome (PEX5 Knockout Mouse)

Zellweger syndrome (cerebro-hepato-renal syndrome) is the most severe form of the peroxisomal biogenesis disorders leading to early death of the affected children. To study the pathogenetic mechanisms causing organ dysfunctions in Zellweger syndrome, we have recently developed a knockout-mouse model...

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Hlavní autoři: Baumgart, Eveline, Vanhorebeek, Ilse, Grabenbauer, Markus, Borgers, Marcel, Declercq, Peter E., Fahimi, H. Dariush, Baes, Myriam
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850512/
https://ncbi.nlm.nih.gov/pubmed/11583975
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