Urokinase-Receptor/Integrin Complexes Are Functionally Involved in Adhesion and Progression of Human Breast Cancer in Vivo

Interactions between specific cell-surface molecules, which include the urokinase receptor (uPAR) and integrins, are crucial to processes of tumor invasion and metastasis. Here we demonstrate that uPAR and β1-integrins may cluster at distinct sites at the cell surface of metastatic MDA-MB-231 breast...

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Main Authors: van der Pluijm, Gabri, Sijmons, Bianca, Vloedgraven, Hans, van der Bent, Chris, Drijfhout, Jan-Wouter, Verheijen, Jan, Quax, Paul, Karperien, Marcel, Papapoulos, Socrates, Löwik, Clemens
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850470/
https://ncbi.nlm.nih.gov/pubmed/11549590
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