Plasmacytoid Dendritic Cells (Natural Interferon- α/β-Producing Cells) Accumulate in Cutaneous Lupus Erythematosus Lesions

Plasmacytoid dendritic cell (P-DC) precursors in peripheral blood produce large amounts of interferon (IFN)-α/β when triggered by viruses. However, when incubated with interleukin-3 and CD40 ligand, the same precursors differentiate into mature DCs that stimulate naïve CD4(+) T cells to produce Th2...

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Autori principali: Farkas, Lorant, Beiske, Klaus, Lund-Johansen, Fridtjof, Brandtzaeg, Per, Jahnsen, Frode L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2001
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850412/
https://ncbi.nlm.nih.gov/pubmed/11438470
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