The Transmembrane Form of the CX3CL1 Chemokine Fractalkine Is Expressed Predominantly by Epithelial Cells in Vivo

Fractalkine (CX3CL1) is synthesized as a type I transmembrane protein. Its unique CX(3)C chemokine domain is attached to a 241-amino acid mucin stalk, a 19-amino acid transmembrane domain, and a 37-amino acid intracellular domain of unknown function. A soluble form of fractalkine can be generated by...

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Bibliographic Details
Main Authors: Lucas, Andrew D., Chadwick, Nicholas, Warren, Bryan F., Jewell, Derek P., Gordon, Siamon, Powrie, Fiona, Greaves, David R.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850344/
https://ncbi.nlm.nih.gov/pubmed/11238035
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