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The Characterization of Mice with a Targeted Combined Deficiency of Protein C and Factor XI
Activated protein C functions directly as an anticoagulant and indirectly as a profibrinolytic enzyme. To determine whether the fibrin deposition previously observed in PC(−/−) murine embryos and neonates was mediated through the FXI pathway, PC(+/−)/FXI(−/−) mice were generated and crossbred to pro...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850297/ https://ncbi.nlm.nih.gov/pubmed/11159184 |
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