CDKN2A Mutation Analysis, Protein Expression, and Deletion Mapping of Chromosome 9p in Conventional Clear-Cell Renal Carcinomas : Evidence for a Second Tumor Suppressor Gene Proximal to CDKN2A

Inactivation of tumor suppressor genes on chromosome 9p is considered a critical event in renal cell carcinoma pathogenesis. Alterations of CDKN2A on 9p21 have been reported in renal cancer cell lines, but their relevance for primary renal carcinomas is unclear. Loss of heterozygosity (LOH) was anal...

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Detaylı Bibliyografya
Asıl Yazarlar: Schraml, Peter, Struckmann, Kirsten, Bednar, Rudolf, Fu, Wenting, Gasser, Thomas, Wilber, Kim, Kononen, Juha, Sauter, Guido, Mihatsch, Michael J., Moch, Holger
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2001
Konular:
Regular Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850295/
https://ncbi.nlm.nih.gov/pubmed/11159196
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