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Constitutively active β-catenin confers multi-lineage differentiation potential on lymphoid and myeloid progenitors
β-catenin mediated Wnt signaling may contribute to the self-renewal of hematopoietic stem cells and proliferation in some malignancies. We now show that expression of constitutively active β-catenin in normal lymphoid or myeloid progenitors generated uncommitted cells with multi-lineage differentiat...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850237/ https://ncbi.nlm.nih.gov/pubmed/16356858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2005.10.009 |
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