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The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny

Nuclear and cytoplasmic protein glycosylation is a widespread and reversible posttranslational modification in eukaryotic cells. Intracellular glycosylation by the addition of N-acetylglucosamine (GlcNAc) to serine and threonine is catalyzed by the O-GlcNAc transferase (OGT). This “O-GlcNAcylation”...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Shafi, Raheel, Iyer, Sai Prasad N., Ellies, Lesley G., O'Donnell, Niall, Marek, Kurt W., Chui, Daniel, Hart, Gerald W., Marth, Jamey D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18502/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10801981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100471497
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