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CD8(+) T Cells in Hodgkin’s Disease Tumor Tissue Are a Polyclonal Population with Limited Clonal Expansion but Little Evidence of Selection by Antigen

A minor component (about 25%) of lymphocytes in Hodgkin’s disease (HD) are CD8(+) T cells. It is unclear whether the presence of these cells reflects an antitumor cytotoxic response. The goal of the present study was to investigate clonal composition and the T cell receptor (TCR) β repertoire of the...

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Bibliografiska uppgifter
Huvudupphovsmän: Willenbrock, Klaus, Roers, Axel, Blöhbaum, Birgit, Rajewsky, Klaus, Hansmann, Martin-Leo
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850194/
https://ncbi.nlm.nih.gov/pubmed/10880387
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