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Mediation of aldose reductase in lipopolysaccharide –induced inflammatory signals in mouse peritoneal macrophages.

Aldose reductase (AR; AKR1B1) a member of aldoketo reductase super family, that we had shown earlier mediates cytotoxic signals induced by high glucose, cytokines and growth factors, also mediates the inflammatory signals induced by Gram-negative bacterial endotoxin, lipopolysaccharide (LPS). Inhibi...

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Bibliographic Details
Main Authors: Ramana, Kota V, Srivastava, Satish K
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850149/
https://ncbi.nlm.nih.gov/pubmed/17174561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2006.11.003
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