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Relationship between glycogen accumulation and the laforin dual specificity phosphatase

Laforin, encoded by the EPM2A gene, is a dual specificity protein phosphatase that has a functional glycogen binding domain. Mutations in the EPM2A gene account for around half of the cases of Lafora disease, an autosomal recessive neurodegenerative disorder, characterized by progressive myoclonus e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Wei, Parker, Gretchen E., Skurat, Alexander V., Raben, Nina, DePaoli-Roach, Anna A., Roach, Peter J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850102/
https://ncbi.nlm.nih.gov/pubmed/17022935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.09.091
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