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Complement C5b-9-Mediated Arachidonic Acid Metabolism in Glomerular Epithelial Cells : Role of Cyclooxygenase-1 and -2

In the passive Heymann nephritis (PHN) model of membranous nephropathy, complement C5b-9 induces glomerular epithelial cell (GEC) injury and proteinuria, which is partially mediated by eicosanoids. This study addresses the role of cyclooxygenase (COX)-1 and -2 in C5b-9-mediated eicosanoid production...

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Détails bibliographiques
Auteurs principaux: Takano, Tomoko, Cybulsky, Andrey V.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850096/
https://ncbi.nlm.nih.gov/pubmed/10854230
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