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Selection of Streptomyces ambofaciens mutants that produce large quantities of spiramycin and determination of optimal conditions for spiramycin production.

The aim of this work was to develop a strategy to isolate a morphologically stable mutant of Streptomyces ambofaciens ATCC 15154 which produced high titers of spiramycin. The rationale was to grow a nitrosoguanidine-mutated population for many generations under nonselective conditions followed by tw...

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Vydáno v:Appl Environ Microbiol
Hlavní autoři: Ford, L M, Eaton, T E, Godfrey, O W
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185005/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2268160/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.56.11.3511-3514.1990
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