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Indomethacin Prophylaxis for Preterm Infants: the Impact of Two Multicentered Randomized Controlled Trials on Clinical Practice

OBJECTIVES: Two multicentered RCTs in premature infants (Ment et al, 1994 and TIPP, 2001) found beneficial effects of indomethacin prophylaxis on the incidences of patent ductus arteriosus (PDA), PDA ligation, and severe intracranial hemorrhage (ICH). The Ment-trial recommended its use. The TIPP-tri...

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Detalhes bibliográficos
Main Authors: Clyman, Ronald I., Saha, Shampa, Jobe, Alan, Oh, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1849955/
https://ncbi.nlm.nih.gov/pubmed/17188612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpeds.2006.09.001
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