Activity of 1-(2'-fluoro-2'-deoxy-beta-D-arabinofuranosyl)thymine against herpes simplex virus in cell cultures and rabbit eyes.

A new antiviral compound 1-(2'-fluoro-2'-deoxy-beta-D-arabinofuranosyl)thymine (2'-fluoro-5-methyl-ara-uracil [FMAU]), was compared with acyclovir and idoxuridine in vitro against two strains of both herpes simplex virus type 1 (HSV-1) and HSV-2. Determinations of the 50% effective dose varied sligh...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Trousdale, M D, Nesburn, A B, Su, T L, Lopez, C, Watanabe, K A, Fox, J J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1983
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184970/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6311085/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.6.808
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