Production and secretion in Escherichia coli of hepatitis B virus pre-S2 antigen as fusion proteins with beta-lactamase.

The diagnostically important surface antigen pre-S2 of hepatitis B virus was produced in large amounts in the periplasmic space of Escherichia coli. The DNA fragments (pre-S2) coding the pre-S2 antigen were tandemly duplicated or triplicated and ligated in the same reading frame to a fragment contai...

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Detalhes bibliográficos

Publicado no:	Appl Environ Microbiol
Principais autores:	Kadokura, H, Yoda, K, Imai, M, Yamasaki, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2275530/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.56.9.2742-2747.1990
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