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Hob3p, the fission yeast ortholog of human BIN3, localizes Cdc42p to the division site and regulates cytokinesis
Cdc42 GTPase is required for polarization in eukaryotic cells, but its spatial regulation is poorly understood. In Schizosaccharomyces pombe, Cdc42p is activated by Scd1p and Gef1p, two guanine-nucleotide exchange factors. Two-hybrid screening identified Hob3p as a Gef1p binding partner. Hob3p is a...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2007
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847667/ https://ncbi.nlm.nih.gov/pubmed/17363901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601641 |
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