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Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription
Fra-1 is frequently overexpressed in epithelial cancers and implicated in invasiveness. We previously showed that Fra-1 plays crucial roles in RAS transformation in rat thyroid cells and mouse fibroblasts. Here, we report a novel role for Fra-1 as a regulator of mitotic progression in RAS-transforme...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847654/ https://ncbi.nlm.nih.gov/pubmed/17347653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601617 |
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