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Melatonin treatment in old mice enables a more youthful response to LPS in the brain.

Melatonin modulates the expression of a number of genes related to inflammation and immunity. Declining levels of melatonin with age may thus relate to some of the changes in immune function that occur with age. mRNA expression levels in murine CNS were measured using oligonucleotide microarrays in...

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Detalhes bibliográficos
Main Authors: Perreau, V.M., Bondy, S.C., Cotman, C.W., Sharman, K.G., Sharman, E.H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847646/
https://ncbi.nlm.nih.gov/pubmed/17070935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2006.09.005
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