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Identification of Membrane Type-1 Matrix Metalloproteinase as a Target of Hypoxia-Inducible Factor-2α in von Hippel Lindau Renal Cell Carcinoma
Metastatic renal cell carcinoma (RCC) resulting from the hereditary loss of the von Hippel Lindau (VHL) tumor suppressor gene is the leading cause of death in VHL patients due to the deleterious effects of the metastatic tumor(s). VHL functions in the destruction of the alpha subunits of the heterod...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847637/ https://ncbi.nlm.nih.gov/pubmed/15592504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1208305 |
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