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Differential expression of interferon responsive genes in rodent models of transmissible spongiform encephalopathy disease

BACKGROUND: The pathological hallmarks of transmissible spongiform encephalopathy (TSE) diseases are the deposition of a misfolded form of a host-encoded protein (PrP(res)), marked astrocytosis, microglial activation and spongiosis. The development of powerful gene based technologies has permitted i...

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Main Authors: Stobart, Michael J, Parchaliuk, Debra, Simon, Sharon LR, LeMaistre, Jillian, Lazar, Jozef, Rubenstein, Richard, Knox, J David
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847514/
https://ncbi.nlm.nih.gov/pubmed/17367538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-2-5
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